The goal of the DIAMANTE Project is to improve the effectiveness and accessibility of immunotherapy strategies based on CAR‑T cells for people with cancer. To achieve this, the project combines artificial intelligence, next‑generation massive sequencing technologies and advanced gene‑editing technologies in order to comprehensively understand the biological processes that take place during CAR‑T therapies and identify vulnerabilities that can be modulated to enhance their effectiveness. In addition, through innovative developments and new delivery systems based on non‑viral technologies and nanoparticles, the DIAMANTE Project will contribute to the development of new CAR‑T medicines with lower toxicity and higher efficacy, increasing their accessibility by reducing production costs.
Call: Grants for carrying out strategic R&D projects in 2023–2026 from the Government of Navarra
Type of action: GEMA VII. Personalised medicine and advanced therapies.
Proposal number: 0011-1411-2023-000051
Proposal acronym: DIAMANTE
Duration (months): 28
Proposal title: Development of Innovative CAR‑T‑based Medicines: Data, Artificial Intelligence, Massive Sequencing and Nanotechnology.
Total funding: 1.155.906,52€
07/01/2023 - 12/31/2025